Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVFLIGANGQIGQRLVS-LFQDNPDHSIRAMVRKEEQKASLEAAGAEAVLANLEGSPEEIAAAAKGCDAIIFTAGSGGSTGYDKTLLVDLDGAAKAIEAAAIAGIKRFIMVSALQAHNRENWNEALKPY---YVAKHYADKILEASGLTYTIIRPG---------GLR--NEPGTGTVSAAKDLERGFISRDDVAKTVIASLDEKNTENRAFDLTEGDTPIAEALKKL 2JL1 Chain:A ((1-198)) FSIAVTGATGQLGGLVIQHLLKKVPASQIIAIVRNVEKASTLADQGVEVRHGDY-NQPESLQKAFAGVSKLLFISGP----HYDNTLLIVQH--ANVVKAARDAGVKHIAYTGYAFA------EESIIPLAHVHLATEYA---IRTTNIPYTFLRNALYTDFFVNEGLRASTESGAIVTNAGSGIVNS-VTRNELALAAATVLTEEGHENKTYNL--------------

General information: TITO was launched using: RESULT: Template: 2JL1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 865 -123214 -142.44 -673.30 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -142.44 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.569

(partial model without unconserved sides chains): PDB file : Tito_2JL1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2JL1-query.scw PDB file : Tito_Scwrl_2JL1.pdb: