Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADTLERVTKIIVDRLGVDEADVKLEASFKEDLGADSLDVVELVMELEDEFDMEISDEDAEKIATVGDAVNYIQNQQ 3EJE Chain:A ((20-95)) MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGH-

General information: TITO was launched using: RESULT: Template: 3EJE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 258 -38876 -150.68 -511.53 target 2D structure prediction score : 0.78 Monomeric hydrophicity matching model chain A : 0.88 3D Compatibility (PKB) : -150.68 2D Compatibility (Sec. Struct. Predict.) : 0.78 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.774

(partial model without unconserved sides chains): PDB file : Tito_3EJE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EJE-query.scw PDB file : Tito_Scwrl_3EJE.pdb: