Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIGVIDYGMGNLYSVSKALERVGVPYFVSEKPEE--LKEADAFILPGVGSFGDAMDNLGYTKLDQLIHDMVSEGRLLLGICLGMQLLFEESEENGTASGLGLLKGKAVRLKAEDEKGNKLKVPHMGWNRLSFHNESPLLTKTEQGYAYFVHSYYI-------DGMEENAL-LASADYGV-RVPAVVGKRNVFGAQFHPEKSSTVGMSILTQFTKMAAEQKVKK 1OX6 Chain:A ((6-238)) VVHVIDVESGNLQSLTNAIEHLGYEVQLVKSPKDFNISGTSRLILPGVGNYGHFVDNLFNRGFEKPIREYIESGKPIMGICVGLQALFAGSVESPKSTGLNYIDFKLSRFDDSEK-----PVPEIGWNSC-IPSENLFFGLDPYKRYYFVHSFAAILNSEKKKNLENDGWKIAKAKYGSEEFIAAVNKNNIFATQFHPEKSGKAGLNVIENFLKQQS------

General information: TITO was launched using: RESULT: Template: 1OX6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1051 -27212 -25.89 -136.06 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -25.89 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.517

(partial model without unconserved sides chains): PDB file : Tito_1OX6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OX6-query.scw PDB file : Tito_Scwrl_1OX6.pdb: