Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWGGREEYRAVKPGTPGIQPKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADPRRHRELDGSGTVRGNIKVPAKLVVGSKFSTKMKLFGLPYRITSRVTALKPNELVEWSH---PLG-HRWRWEFESLSPTLTRVTETFDYHAAGAIKNGLKFYEMTGFAKSNAAGIEATLAKLSDQYARGRA 2D4R Chain:A ((3-146)) ----------------------------------------------------------------------------EVRAERYIPAPPERVYRLAKDLEGLKPYLKE--VESLEVVARE-GARTRSRWVAVAMGKKVRWLEEEEWDDENLRNRFFSPEGDFDRYEGTWVFLPEGE-GTRVVLTLTYELTIPIF--GGLLRKL-VQKLMQENVESLLKGLEERVLAAS-

General information: TITO was launched using: RESULT: Template: 2D4R.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -23995 for 1019 contacts (-23.5/contact) + 2D Compatibility (PS) -15144 + (NN) -3574 + (LL) 3424 1D Compatibility (HY) -3200 + (ID) 1050 Total energy: -43539.0 ( -42.73 by residue) QMean score : 0.343

(partial model without unconserved sides chains): PDB file : Tito_2D4R.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D4R-query.scw PDB file : Tito_Scwrl_2D4R.pdb: