Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRRRLAIVQRWRGQDEIPTDWGRCVLTIGVFDGVHRGHAELIAHAVKAGRARGVPAVLMTFDPHPMEVVYPGSHPAQLTTLTRRAELVQDLGIEVFLVMPFTTDFMK---LTPDRFIHELLVEHLHVVEVVVGENFTFGKKAAGNVDTLRRAGERFGFAVESMSLVSEHHSNETVTFSSTYIRSCVDAGDMVAAMEALGRPHRVEGVVVRGEGRGAELGFPTANVAPPMYSAIPAD-GVYAAWFTVLGHGPVTGTVVPGERYQAAVSVGTNPTFSGRTRTVEAFVLDTTADLYGQHVALDFVGRIRGQKKFESVRQLVAAMGADTERARDLLSTG 1MRZ Chain:A ((2-282)) ------------------------VVSIGVFDGVHIGHQKVLRTMKEIAFFRKDDSLIYTI-SYPPEYFLP-DFPGLLMTVESRVEMLSRYARTVVL------DFFRIKDLTPEGFVERYLS---GVSAVVVGRDFRFGKNASGNASFLRKKGVEV-YEIEDVVVQGKR-------VSSSLIRNLVQEGRVEEIPAYLGRYFEIEGIV-----------FPTANIDRGNEKLVDLKRGVY----LVRVHLP------DGKKKFGVMNVGFR-----RNVKYEVYILDFEGDLYGQRLKLEVLKFMRDEKK----EELKAAIDQDVKSARNMID--

General information: TITO was launched using: RESULT: Template: 1MRZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -171296 for 1949 contacts (-87.9/contact) + 2D Compatibility (PS) -27165 + (NN) -3759 + (LL) 4032 1D Compatibility (HY) -24000 + (ID) 4550 Total energy: -226738.0 ( -116.34 by residue) QMean score : 0.448

(partial model without unconserved sides chains): PDB file : Tito_1MRZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1MRZ-query.scw PDB file : Tito_Scwrl_1MRZ.pdb: