Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTFARLAAGLCICAIASQANAWSQPTHKNIVKDALAFMNSSYATEEMRQAYRFYVSAAGSEAQAGEILGQAAFDVDDFKDTRLGGWWVGYEHAPLWGAASGIVNYTSYWHFLNLARDGDSHGNPHGGYDYRYHKVDGGIADVDWYAMVYLYNRELKREDFDTTEAHYRQGT---RSDWQEHYGDFQTAAFQPIDNLATYWFEQFRAAPSLQTIGYALHATGDVAQPHH---VWITSANGHSSWEGWVDDHYASEKLNDPAAVANLVGRYDPSKSIRDLLTQTGQVAYARPEPLYDTSYETRLRVAKELIPESIALTVTVLTKGANSFDAPTAL 1GYG Chain:A ((92-165)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------DTGESQIRKFSALARYEWQR--GNYKQATFY---------------------LGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTVGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLH

General information: TITO was launched using: RESULT: Template: 1GYG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 7455 for 332 contacts (22.5/contact) + 2D Compatibility (PS) -7296 + (NN) -1130 + (LL) 11772 1D Compatibility (HY) -2400 + (ID) 1150 Total energy: 7251.0 ( 21.84 by residue) QMean score : 0.101

(partial model without unconserved sides chains): PDB file : Tito_1GYG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GYG-query.scw PDB file : Tito_Scwrl_1GYG.pdb: