Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCS-RRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF 4BTK Chain:A ((50-335)) --------ANYVVKDRWKVLKKIGGG---EIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTG-DVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKD---KEQVGMIKEKYE---HRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE--------------------------------------

General information: TITO was launched using: RESULT: Template: 4BTK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -153481 for 2217 contacts (-69.2/contact) + 2D Compatibility (PS) -29474 + (NN) -9562 + (LL) 2208 1D Compatibility (HY) -23600 + (ID) 5000 Total energy: -218909.0 ( -98.74 by residue) QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_4BTK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BTK-query.scw PDB file : Tito_Scwrl_4BTK.pdb: