Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENVFDYEDIQLIPAKCIVNSRSECDTSVRLGGH-TFKLPVVPANMQTIIDEKLAISLAENGYFYVMHR-FEPETRI-DFIKDMNARGLFSSISVGVKDEEYEFVRQLAEENLTPEYVTIDIAHGHSNAVIEMIQHLKKHLPDSFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASK---PIIADGGIRTHGDIAKSIRFGATMVMIGSLFAGHEESPGQTIEKDGKLYKEYFGSAS-----EFQKGEKKN--VEGKKMHVAHKGSIKDTLIEMEQDLQSSISYAGGTKLNAI-RNVDYVIVKNSIFNGDKY 3KHJ Chain:B ((13-339)) ----LTFEDILLVPNYSEVLPR-EVSLETKLTKNVSLKIPLISSAMDTVTEHLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGGLRVGAAIGVN--EIERAKLLVEAGV--DVIVLDSAHGHSLNIIRTLKEIKSKM-NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGV--PQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMK---------MVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEITT--------

General information: TITO was launched using: RESULT: Template: 3KHJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1845 -4797 -2.60 -16.15 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -2.60 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.578

(partial model without unconserved sides chains): PDB file : Tito_3KHJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KHJ-query.scw PDB file : Tito_Scwrl_3KHJ.pdb: