Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE 2VTH Chain:A ((4-287)) -----FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIR------------STAIREISLLKELN---HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAF----------VTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVP

General information: TITO was launched using: RESULT: Template: 2VTH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -187993 for 2058 contacts (-91.3/contact) + 2D Compatibility (PS) -27959 + (NN) -17522 + (LL) 816 1D Compatibility (HY) -30800 + (ID) 6500 Total energy: -269958.0 ( -131.17 by residue) QMean score : 0.566

(partial model without unconserved sides chains): PDB file : Tito_2VTH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VTH-query.scw PDB file : Tito_Scwrl_2VTH.pdb: