Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTAIVAAITAQIQKA---KLPTHVEIDAKRYGFERDSVILLEQIRTIDKQRLTDKITHLDDEMMDKVDEALQISLALIDF 3VUB Chain:A ((12-99)) ---------------------SRYRLFVDVQSDIIDT-PGRRMVIPLASARLLSDKVSRELYPVVHI--G--DESWRMMTTDMASVPVSVIGEEVADLS-HRENDIKNAINLMFW----

General information: TITO was launched using: RESULT: Template: 3VUB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 292 -55557 -190.26 -653.61 target 2D structure prediction score : 0.45 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -190.26 2D Compatibility (Sec. Struct. Predict.) : 0.45 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.514

(partial model without unconserved sides chains): PDB file : Tito_3VUB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3VUB-query.scw PDB file : Tito_Scwrl_3VUB.pdb: