Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MINVLIVEDDPMVGELNKRYLSQIDGFQLKGIASSFQSALHILGEHHIDLILLDIYMPGKNGLELLTELRAQNEAVDVIVISAASELDVIKKTLRYGAVDYLIKPFEFERFQTALSDYRRKQKVYSTHRNMSQKELDAELFQKKEATEKVQLPKGLTKSTLKLIWSSIQSFENESFTTEDLAKH-----TEISQVSIRKYLKFLEDIQVLNVEMAYGTIGRPVFQYNVNNSNINGIKQYL 3Q9S Chain:A ((5-205)) --RILVIEDDHDIANVLRMDLTD-AGYVVD-HADSAMNGLIKAREDHPDLILLDLGLPDFDGGDVVQRLRKN-SALPIIVLTARDTVEEKVRLLGLGADDYLIKPFHPDELLARVKVQLRQRTSESL--SMGDLTLD----PQKRLVTYKGEELRLSPKE-FDILALLIRQPGRVYSRQEIGQEIWQGRLPEGSNVVDVHMANLRAKLRDLDG---------------------------

General information: TITO was launched using: RESULT: Template: 3Q9S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 885 -71753 -81.08 -366.09 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -81.08 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_3Q9S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3Q9S-query.scw PDB file : Tito_Scwrl_3Q9S.pdb: