Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYLG 2D5K Chain:A ((3-148)) -------SNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS

General information: TITO was launched using: RESULT: Template: 2D5K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 616 -53275 -86.48 -364.89 target 2D structure prediction score : 0.79 Monomeric hydrophicity matching model chain A : 0.85 3D Compatibility (PKB) : -86.48 2D Compatibility (Sec. Struct. Predict.) : 0.79 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.529

(partial model without unconserved sides chains): PDB file : Tito_2D5K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2D5K-query.scw PDB file : Tito_Scwrl_2D5K.pdb: