Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGAR--GVIRLLDWFERPDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQD------EEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGVPESCDLRLCTLDPDDVASTTSSSESL 2WTW Chain:A ((15-271)) ---------------------------------------FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG--------VEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYA-PRGEVYKELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG-SAGELKIADFGWSVHAPS------CGTLDYLPPEMIE-GRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPW-ITANSSK--------------------------

General information: TITO was launched using: RESULT: Template: 2WTW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -159187 for 1897 contacts (-83.9/contact) + 2D Compatibility (PS) -26211 + (NN) -13929 + (LL) 4080 1D Compatibility (HY) -20000 + (ID) 4150 Total energy: -219397.0 ( -115.65 by residue) QMean score : 0.480

(partial model without unconserved sides chains): PDB file : Tito_2WTW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WTW-query.scw PDB file : Tito_Scwrl_2WTW.pdb: