Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIV--NYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRPDEDLRNCESDTEEDIARRKALHPRRRSSTS 2WEI Chain:A ((24-286)) ----------------------YNIVCMLGKGSFGEVLKCKDRITQQEYAVKVINK----ASAKNKDTSTILREVELLKKLDHPNIMKLFEILEDSSSFYIVGELYTGGELFDEIIKRKRFSEHDAARIIKQVFSGITYMHKHNIVHRDLKPENILLESKEKDCD-IKIIDFGLSTCFQQNTKMKDRIGTAYYIAPEVLRGTYDE---KCDVWSAGVILYILLSGTPPFYGKNEYDILKRVETGKYAFDLPQWRTISDDAKDLIRKMLTFHPSLRITATQCLEHPWIQKYSSE-------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2WEI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -127125 for 2077 contacts (-61.2/contact) + 2D Compatibility (PS) -27618 + (NN) -5227 + (LL) 8332 1D Compatibility (HY) -24800 + (ID) 5150 Total energy: -181588.0 ( -87.43 by residue) QMean score : 0.481

(partial model without unconserved sides chains): PDB file : Tito_2WEI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2WEI-query.scw PDB file : Tito_Scwrl_2WEI.pdb: