Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVR-HAQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF--FTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG 2VTM Chain:A ((1-294)) MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKI--------VPSTAIREISLLKEL-NHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVP-VRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDY-KPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2VTM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -203116 for 2275 contacts (-89.3/contact) + 2D Compatibility (PS) -29753 + (NN) -15684 + (LL) 1736 1D Compatibility (HY) -32000 + (ID) 6400 Total energy: -285217.0 ( -125.37 by residue) QMean score : 0.570

(partial model without unconserved sides chains): PDB file : Tito_2VTM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VTM-query.scw PDB file : Tito_Scwrl_2VTM.pdb: