Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSRIEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGRIPVVSTLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDR-DSLVSEIDTGTLAQLLPT--LESGMVPKVEACLRAVIGGVPSAHIIDGRVTHCVLVELFTDAGTGTKVVRG 2V5H Chain:A ((28-310)) ------AGAADRVRILSEALPYLQQFAGRTVVVKYGGAAMKQEELKEAVMRDIVFLACVGMRPVVVHGGGPEINAWLGRVGIEPQFHNGLRVTDADTMEVVEMVLVGRVNKDIVSRINTTGGRAVGFCGTDGRLVLARPH------DQEGIGFVGEVNSVNSEVIEPLLERGYIPVISSVAADENGQSFNINADTVAGEIAAALNAEKLILLTDTRGILE-DPKRPESLIPRLNIPQSRELIAQGIVGGGMIPKVDCCIRSLAQGVRAAHIIDGRIPHALLLEIFTDAGIGTMIVG-

General information: TITO was launched using: RESULT: Template: 2V5H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -227940 for 2407 contacts (-94.7/contact) + 2D Compatibility (PS) -31065 + (NN) -16543 + (LL) 820 1D Compatibility (HY) -28400 + (ID) 6350 Total energy: -309478.0 ( -128.57 by residue) QMean score : 0.546

(partial model without unconserved sides chains): PDB file : Tito_2V5H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V5H-query.scw PDB file : Tito_Scwrl_2V5H.pdb: