Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRRILSILVFAIMLAGCSSNASTEKQHAGGEKTVKAEPQSTSSQKDSTDDYQPNSQVTDDRTLHKVGQTFSDDKGKAVLKDIKQVNKTYKIGDVELTVKEMKLIHLRPDYSMIDYFHELTHDEEFDFVKVFVDIK--------NTSTKKV-------NVAPIALMKT-------NTGETFDWNKD-----IYLEELNGELEGGAEKSGNLGFIVNASSGH--AHDKAAD----AEKKTKEIK-WIEITTSDVFDHNHKK----------ISDAQKIKIKF-- 4CIJ Chain:A ((1-267)) MSGLKPCVDWLQVTFK-TGQDSVKKCVEKLEKVFEILGLN-------EAEFLP---LKNGKYGYKQGVAFQGNPVLAVYYDGADDMG----IHVEMTGQGCRLFELHTSINWYELFYRLVYEYEVNITRLDVAVDDFKGYFKINTLVKKLKDDEVTSRFKKARHIENIVIEGGETIGHTLYFGAPSSDIQVRFYEKNVQMGMDIDVWNRTEIQLRDDRAHVVAQIIADDVLPLGEIVAGLLRNYIQFRTRKATDKNKKRWPLARFWLNFLGDVQPLRIAKQM

General information: TITO was launched using: RESULT: Template: 4CIJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 999 -67640 -67.71 -306.06 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -67.71 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.238

(partial model without unconserved sides chains): PDB file : Tito_4CIJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CIJ-query.scw PDB file : Tito_Scwrl_4CIJ.pdb: