Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKPLVGINMKNYINTRAQTSEWLEATIPLLGNFSDVDTFIFPSMGTLETTANLLAGTSFGFGPQNMAPEKSGPLTGEFSVESIIDLSANYVEIGHAERKNLFHEKTSEIAKKIQLALDEKITPVVCVGEGIRANDTNELKNALKKQIEALFDTIQVTQFKNVVLAYEPEWAIGKANSADTDYIESAHQALREII-RELGGD-ETLVRIIYGGSVSKENAAEIVRQKNVDGLFVGRFGHKPQNFADIVSIVSKTKG 4MKN Chain:A ((52-262)) ------------------------------------VDVVVAPPFIYIDYVMQHLDRDKYQLSAQNAWIGGNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAAGLGVIACIGETLEQRNSGSVFKVLDAQMDALVD--EVKDWTKVVLAYEPVWAIGTGVVASPEQAQEVHAYLRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKGAAFVTICN-------

General information: TITO was launched using: RESULT: Template: 4MKN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -95032 for 1644 contacts (-57.8/contact) + 2D Compatibility (PS) -22642 + (NN) -7198 + (LL) 2960 1D Compatibility (HY) -16400 + (ID) 3500 Total energy: -141812.0 ( -86.26 by residue) QMean score : 0.481

(partial model without unconserved sides chains): PDB file : Tito_4MKN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MKN-query.scw PDB file : Tito_Scwrl_4MKN.pdb: