Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFQKKTYAVFLILLLMMFTAACSGSKTSAEKKESETEKSSDIAQVKIKDVSYTLPSKYDKSTSDDQLVLKVNVAVKNTGKDPLNVDS---MDFTLYQGDTKMSDTDPEDYSEKLQGSTINADKSVEGNLFFVVDKGKQYELNYTPESYGDKKPKSVTFKIDGKDKKILATADKLQDSAKALSAYVDVLLFGKDNADFEKITGANKNEIVNDFNESAKDGYLSASGLSSTYADSKALDNIVNGIKEGLSKNSSIQAKTTSISKDEAIVEATVKPVDASSLSDRIEDKVKDYYSKNSSASYEEAVKYALQVYPEEFKKLGPASSEKTVEVKMKKNDIDQWQLDMDDYRAAELVEAFIKE 3JZ0 Chain:A ((22-287)) --------------------------------------------LKQKELIANVKNLTESDE-------RITACMMYGSFTKGEGDQYSDIEFYIFLKHSITSNFDSSNWLFDV-APYLMLYKNEYGTEVVIFDNLIRGEFHFLS-------------------EKDMNIIPSFKDS-GYIPDTKAMLIYDETG-QLENYLSEISGARPNRLTEENANFLLCNFSNLWLMGINVLKRGEYARSLELLSQLQKNTLQLIRMAEKNADNWLNMSKNLEKEISLENYKKFAKTTARLDKVELFEAYKNSLLLVMDLQSHLIEQYNLKV------------------THDILERLLNYISE

General information: TITO was launched using: RESULT: Template: 3JZ0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1131 -75806 -67.03 -288.24 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -67.03 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.273

(partial model without unconserved sides chains): PDB file : Tito_3JZ0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3JZ0-query.scw PDB file : Tito_Scwrl_3JZ0.pdb: