Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEMMGMENIQQNQGLKQKDEQFVWHAMKGAHQADSLIAQKAEGAWVTDTDGRRYLDAMSGLW-CVNIGYGRKELAEAAYEQLKELPYYP-LTQSHAPAIQLAEKLNEWLGGD--YVIFFSNSGSEANETAFKIARQYHLQNGDHSRYKFISRYRAYHGNTLGALSATGQAQRKYKYEPLSQGFLHAAPPDIYRNPDDADTLESANEIDRIMTWELSETIAGVI----MEPIITGGGILMPPDGYMKKVEDICRRHGALLICDEVICGFGRTGEPFGFMHYGVKPDIITMAKGITSAYLPLSATAVKRDIFEAYQGEAPYDRFRHVNTFGGSPAACALALKNLQIMEDEQLIQRSRDLGAKLLGELQAL-REHPAVGDVRGKGLLIGIELVKDKLTKEPADAAKVNQVVAACKEKGLI---IGKNGDTVAGYNNVIQLAPPFCLTEEDLSFIVKTVKESFQTI 3DXV Chain:B ((33-425)) -----------------------------------------RGARLIEENGRELID-LSGAWGAASLGYGHPAIVAAVSAAAANPAGATILSASNAPAVTLAERLLASFPGEGTHKIWFGHSGSDANEAAYRAIVKATGRSG------VIAFAGAYHGCTVGSMAFSGHSVQADAAK--ADGLILLPYPDPYR-PYRND--PTGDAILTLLTEKLAAVPAGSIGAAFIEPIQSDGGLIVPPDGFLRKFADICRAHGILVVCDEVKVGLARSGRLHCFEHEGFVPDILVLGKGLGGGLP-LSAVIAPAEILDCASAFA-------MQTLHGNPISAAAGLAVLETIDRDDLPAMAERKGRLLRDGLSELAKRHPLIGDIRGRGLACGMELVCDRQSREPAR-AETAKLIYRAYQLGLVVYYVGMNG-------NVLEFTPPLTITETDIHKALDLLDRAFSEL

General information: TITO was launched using: RESULT: Template: 3DXV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2243 -202410 -90.24 -531.26 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.76 3D Compatibility (PKB) : -90.24 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.540

(partial model without unconserved sides chains): PDB file : Tito_3DXV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DXV-query.scw PDB file : Tito_Scwrl_3DXV.pdb: