Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLDTQQIKEIIPHRYPFLLVDRITEVEEGKRAKGYKNVTANEEFFNGHFPQYPVMPGVLIVEALAQVGAVAMLIKEEN-RGRLAFFAGIDNCRFKKQVKPGDQLHLEVEIIRARGTIGRGK--GVATVDGEVVCEV-ELTFALGE 3AZ8 Chain:Q ((11-152)) -IDIEDIKKILPHRYPFLLVDKVIYMQPNKTIIGLKQVSTNEPFFNGHFPQKQIMPGVLQIEALAQLAGILCLKSDDSQKNNLFLFAGVDGVRWKKPVLPGDTLTMQANLISFK---GIAKLSGVGYVNGKVVINISEMTFAL--

General information: TITO was launched using: RESULT: Template: 3AZ8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain Q - contact count / total energy / energy per contact / energy per residue : 623 -35897 -57.62 -265.90 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain Q : 0.83 3D Compatibility (PKB) : -57.62 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.578

(partial model without unconserved sides chains): PDB file : Tito_3AZ8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AZ8-query.scw PDB file : Tito_Scwrl_3AZ8.pdb: