Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIMLTPMQTEEFRSYLTYTTKHYAEEKVKAGTWLPEDAQLLSKQVFTDLLPRGLETPHHHLWSLKL-NEKDIVGWLWIHAEPE--HPQQEAFIYDFGLYEPYRGKGYAKQALAALDQAARSMGIRKLSLHVFAHNQTARKLYEQTGFQETDVVMSKKL 1VKC Chain:A ((10-158)) --EYTIVDGEEYIEEIKKLDREISYSFV--RFPISYEEYEERHEELFESLL----SQGEHKFFVALNER-SELLGHVWICITLDTVDYVKIAYIYDIEVVKWARGLGIGSALLRKAEEWAKERGAKKIVLRVEIDN-PAVKWYEERGYKARALIMEKPI

General information: TITO was launched using: RESULT: Template: 1VKC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 546 -49120 -89.96 -336.44 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -89.96 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_1VKC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VKC-query.scw PDB file : Tito_Scwrl_1VKC.pdb: