Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAVALPRVSGGHDEHGHLEEFRTDPIGLMQRVRDECGDVGTFQLAGKQVVLLSGSHANEFFFRAGDDDLDQAKAYP-FMTPIFGEGVVFDASPERR--KEMLHNAALRGEQMKGHAATIEDQVRRMIADWGE-------AGEIDLLDFFAELTIYTSSACLIGKKFRDQLDGRFAKLYHELERGTDPLAYVDPYLPIESFRRRDEARNGLVALVADIMNGRIANPPTDKSDRDMLDVLIAVKAETGTPRFSADEITGMFISMMFAGHHTSSGTASWTLIELMRHRDAYAAVIDELDELYGDG-RSVSFHALRQIPQLENVLKETLRLHPPLIILMRVAKGEFEV--QGHRIHEGDLVAASPAISNRIPEDFPDPHDFVPARYEQPRQED---------------LLNRWTWIPFGAGRHRCVGAAFAIMQIKAIFSVLLREYEFEMAQPPESYRNDHSKMVVQLAQPACVRYRRRTGV 4LXJ Chain:A ((53-526)) --KDRPPLVFYWIPWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAFKSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDTDFAYLYSDLDKGFTPINFVFPNLPLEHYRKRDHAQKAISGTYMSLIKERRKNND--IQDRDLIDSLMKNSTYKDGVKMTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHHPLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNNDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTVPPPDFTSMVTLPTGPAKIIWEKRNP-

General information: TITO was launched using: RESULT: Template: 4LXJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -237972 for 3766 contacts (-63.2/contact) + 2D Compatibility (PS) -48371 + (NN) -26874 + (LL) 348 1D Compatibility (HY) -32800 + (ID) 6400 Total energy: -352069.0 ( -93.49 by residue) QMean score : 0.682

(partial model without unconserved sides chains): PDB file : Tito_4LXJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LXJ-query.scw PDB file : Tito_Scwrl_4LXJ.pdb: