Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGLNTAIATRVNGTPPPEVPIADIELGSLDFWALDDDVRDGAFAT---LRREAPISFWPTIELPGFVAGNGHWALTKYDDVFYASRHPDIFSSYPNITINDQTPELAEYFGSMIVLDDPRHQRLRSIVSRAFTPKVVARIEAAVRDRAHRLVSSMIANNPDRQADLVSELAGPLPLQIICDMMGIPKADHQRIFHWTNVILGFGDPDLATDFDEFMQVSADIGAYATALAEDRRVNHHDDLTSSLVE-AEVDGERLSSREIASFFILLVVAGNETTRNAITHGVLALSRYPEQRDRWWSDFDGLAPTAVEEIVRWASPV-VYMRRTLTQDIELRGTKMAAGDKVSLWYCSANRDESKFADPWTFDLARNPNPHLGFGGGGAHFCLGANLARREIRVAFDELRRQMPDVVATEEPARLL---SQFIHGIKTLPVTWS 2C6H Chain:A ((35-425)) ----------------------------LDLGALGQDFAADPYPTYARLRAEGPAHRVRTPE------GDEVWLVVGYDRARAVLADPRFSKDWRNSTTPLTEAE-AALNHNMLESDPPRHTRLRKLVAREFTMRRVELLRPRVQEIVDGLVDAMLAA-PDGRADLMESLAWPLPITVISELLGVPEPDRAAFRVWTDAFVFPDDPAQA------QTAMAEMSGYLSRLIDSKRGQDGEDLLSALVRTSDEDGSRLTSEELLGMAHILLVAGHETTVNLIANGMYALLSHPDQLAALRADMT-LLDGAVEEMLRYEGPVESATYRFPVEPVDLDGTVIPAGDTVLVVLADAHRTPERFPDPHRFDIRRDTAGHLAF-GHGIHFCIGAPLARLEARIAVRALLERCPDLALDVSPGELVWYPNPMIRGLKALPIRW-

General information: TITO was launched using: RESULT: Template: 2C6H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -201718 for 3130 contacts (-64.4/contact) + 2D Compatibility (PS) -40669 + (NN) -13982 + (LL) 1436 1D Compatibility (HY) -23600 + (ID) 6950 Total energy: -285483.0 ( -91.21 by residue) QMean score : 0.432

(partial model without unconserved sides chains): PDB file : Tito_2C6H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2C6H-query.scw PDB file : Tito_Scwrl_2C6H.pdb: