Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFD---DTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 2BRM Chain:A ((9-264)) ------------------------WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDM-----CPEN--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVF-------------RYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAK--------------------------

General information: TITO was launched using: RESULT: Template: 2BRM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -137198 for 1910 contacts (-71.8/contact) + 2D Compatibility (PS) -25654 + (NN) -713 + (LL) 3740 1D Compatibility (HY) -14800 + (ID) 4150 Total energy: -178775.0 ( -93.60 by residue) QMean score : 0.328

(partial model without unconserved sides chains): PDB file : Tito_2BRM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2BRM-query.scw PDB file : Tito_Scwrl_2BRM.pdb: