Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRKPIIAGNWKMN---KTLGEAVSFVEEVKSSIPAADKAEAVVCAPALFLEKLASAVKGTDLKVG--AQNMHFEESGAFTGEISPVALKDLGVDYCVIGHSERREMFAETDETVNKKAHAAFKHGIVPIICVGETLEEREAGKTNDLVADQVKKGLAGLSEEQVAASVIAYEPIWAIGTGKSSTAKDANDVCAHIRKTVAESFSQEAADKLRIQYGGSVKPANIKEYMAESDIDGALVGGASLEPQSFVQLLEEGQYE 1SW7 Chain:B ((4-244)) -RKFFVGGNWKMNGDKKSLGELIHTLNGAKLS---AD-TEVVCGAPSIYLD---FARQKLDAKIGVAAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDW--SKVVLAYEPVWAIGTGNSSTPQQAQEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPE-FVDII------

General information: TITO was launched using: RESULT: Template: 1SW7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1293 41297 31.94 174.99 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain B : 0.83 3D Compatibility (PKB) : 31.94 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.532

(partial model without unconserved sides chains): PDB file : Tito_1SW7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1SW7-query.scw PDB file : Tito_Scwrl_1SW7.pdb: