Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAIQLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLK---SVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK 4MKN Chain:A ((22-264)) ----FVGGNWKCNGSVANVAKLVDELNAGTIPRGVDVVVAPPFIYIDYVMQHLDRDKYQ---LSAQNAWIGGNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAAGLGVIACIGETLEQRNSGSVFKVLDAQMDALV-----DEVKDWTKVVLAYEPVWAIGTGVVASPEQAQEVHAYLRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKGAAFVTICNAA-

General information: TITO was launched using: RESULT: Template: 4MKN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -81738 for 2013 contacts (-40.6/contact) + 2D Compatibility (PS) -26109 + (NN) -10410 + (LL) 616 1D Compatibility (HY) -22000 + (ID) 5150 Total energy: -144791.0 ( -71.93 by residue) QMean score : 0.535

(partial model without unconserved sides chains): PDB file : Tito_4MKN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MKN-query.scw PDB file : Tito_Scwrl_4MKN.pdb: