Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEVSDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTT-VAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPE-ALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS 3F6X Chain:B ((25-275)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLGQGC-GEVWMGTWNGTTRVAIKTLKPGT-MSPE----AFLQEAQVMKKLRHEKLVQLYAVVSE-EPIYIVTEYMSKGSLLDFLKGEMGKY-LRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI-----------KF-PIKWTAPEAALYGRFTIKSDVWSFGILLTELTT------KGRVPYPGMVNREVLDQVERGYR-------MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTS

General information: TITO was launched using: RESULT: Template: 3F6X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -88650 for 1854 contacts (-47.8/contact) + 2D Compatibility (PS) -25442 + (NN) -8058 + (LL) 11848 1D Compatibility (HY) -18400 + (ID) 4150 Total energy: -132852.0 ( -71.66 by residue) QMean score : 0.394

(partial model without unconserved sides chains): PDB file : Tito_3F6X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3F6X-query.scw PDB file : Tito_Scwrl_3F6X.pdb: