Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTATRGLEGVVATTSSVSSII--DDTLTYVGYDIDDLTENASFEEIIYLLWHLRLPNKKELEELKQQLAKEAAVPQEIIEHFKSYSLENVHPMAALRTAISLLGLLDSEADTMNPEANYRKAIRLQAKVPGLVAAFSRIRKGLEPVEPREDYGIAENFLYTLNGEEPSPIEVEAFNKALILHADHELNASTFTARVCVATLSDIYSGITAAIGALKGPLHGGANEGVMKMLTEIGEVENAEPYIRAKLEKKEKIMGFGHRVYKHGDPRAKHLKEMSKRLTNLTGESKWYEMSIRIEDIVTS--EKKLPPNVDFYSASVYHSLGIDHDLFTPIFAVSRMSGWLAHILEQYDNNRLIRPRADYTGPDKQKFVPIEERA 2P2W Chain:A ((2-364)) --IQKGLEGVKICESSICYLDGINGRLYYRGIPVEELAEKSTFEETAYFLWYGKLPTKSELEEFKRKMADYRELPAEALGILYHLP-KNLHYIDVLKIFLSIH------------EDLREKAIRVASVFPTILAYYYRYSKGKELIRPRKDLSHVENFYYMMFGER--NEKIRLLESAFILLMEQDINASTFAALVIASTLSDLYSCIVGALGALKGPLHGGASEKVPPMLEEIGSEDRVEEFVQKCLKEKRKIMGFGHRVYKTYDPRAVFLKRVLQEHFP---DSKLFRIASKLEEYIVSNKIKNIYPNVDLYSSVLFEELGFPRNMFTALFATARVVGWTAHVIEYVSDNKLIRPTSEYVGPMDVEYIPIERRD

General information: TITO was launched using: RESULT: Template: 2P2W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1735 -2675 -1.54 -7.60 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -1.54 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.586

(partial model without unconserved sides chains): PDB file : Tito_2P2W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2P2W-query.scw PDB file : Tito_Scwrl_2P2W.pdb: