Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFD---DTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 2BRG Chain:A ((9-264)) ------------------------WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMK------EN--IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVF-------------RYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPL-------------------------------

General information: TITO was launched using: RESULT: Template: 2BRG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -140822 for 1925 contacts (-73.2/contact) + 2D Compatibility (PS) -25305 + (NN) 115 + (LL) 4012 1D Compatibility (HY) -15200 + (ID) 4150 Total energy: -181350.0 ( -94.21 by residue) QMean score : 0.345

(partial model without unconserved sides chains): PDB file : Tito_2BRG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2BRG-query.scw PDB file : Tito_Scwrl_2BRG.pdb: