Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTMKQFEIAAIPGDGVGKEVVAAAEKVLHTAAEVHGGLSFSFTAFPWSCDYYLEHGKMMPEDGIHTLTQFEAVFLGAVGNPK---LVPDHISLWGLLLKIRRELELSINMRPAKQMAGIT--SPLLH---PNDFDFVVIRENSEGEYSEVGGRIHRGDDEIAIQNAVFTRKATERVMRFAFELAKKRRSHVTSATKSNGIYHAMPFWDEVFQQTAADYSGIETSSQHIDALAAFFVTRPETFDVIVASNLFGDILTDISSSLMGSIGIAPSANINPSGKYPSMFEPVHGSAPDIAGQGLANPIGQIWTAKLMLDH-FGEEELGAKILDVMEQVTADGIKTRDIGGQS--TTAEVTDEICSRLRKL 3UDU Chain:E ((6-357)) ----TYKVAVLAGDGIGPLVMKEALKILTFIAQKYN-FSFELNEAKIGGASIDAYGVALSDETLKLCEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLKNEIIQKGVDILCVRELTGGIYF---GKQDLGK-ESAYDTEIYTKKEIERIARIAFESARIRKKKVHLIDKANVLASSI-LWREVVANVAKDYQDINLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKG--FGLYEPAGGSAPDIAHLNIANPIAQILSAALMLKYSFKEEQAAQDIENAISLALAQGKMTKDLNAKSYLNTDEMGDCILEILKE-

General information: TITO was launched using: RESULT: Template: 3UDU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 1929 -196390 -101.81 -575.92 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain E : 0.76 3D Compatibility (PKB) : -101.81 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.481

(partial model without unconserved sides chains): PDB file : Tito_3UDU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3UDU-query.scw PDB file : Tito_Scwrl_3UDU.pdb: