Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQ-PPKKEA-----EKMDERFEKIYTQGKLNIMEIWVDKETGVQYVYHFAGYAGGMSPLLDVDGKPLLADLSKL-NGAE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 4O5P Chain:A ((5-815)) NFGFHIAPTHPVAGRLTYDSKKLSENILKQQSDERVFSRAQCCKAIHITLGFDGTNNNDKADGSSVSPSCSNVARLIHASIGSGDDINSRGIFKYYCPGVGTVFPDIKEFTPSNMGLIGAEGGENRINWGLVQLVDALFYTLLKSRLKLNDVQGLVEEMSTNWTVSTLTGGLLENGEKKRRAALEPKLKELEEKLRQRQNSGQKPHILAMRLYIYGFSRGAAEARAFANWLQELTRVSDADGRVEYRFAGLPISIEFLGLFDTVAAVGLPFAAGHMDWADDTMRLPDEALPEDCSFLKRCVHLVSCHEQRASFPLDSIRRRDMNGRRTGPSCYRKWTVEYAYPGVHSDVGGGYGVGNQGKAVGGSEFLLSQIALQHMYAEAFEAGAPLQVPEWRVMVPKIEAEFSVSEELATRFNAWQAQAKAGPLEEVIRRETALITAWRIDRYAGGLRN------KAFFANVPPDMPEAQQKAWEALHKRRSREYAAAQQLPPMSAAEQAEWDRNVALIGGEDQLRDLRVEKQFDPPLDQRQLLGAAAEFAHDYKGDWGVLDDGMTVGGVIDLLLGGTVFLINEEDEAEEYSQIHRDGSARYHQLFSAPDRVAPGQEKLVALFDEQVHDSRAPFTDYFRYRLVHFDNESNKRLSVLATAGRVVGVGVMLASVGLSVKRRDPRMLLGGLPEISAFDPLTGIALPMVGGAALDNLRAFTREPGDKVEQIGQLPPPPPLAVAAVQSPALQQVLLAQQTV

General information: TITO was launched using: RESULT: Template: 4O5P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 3801 for 258 contacts (14.7/contact) + 2D Compatibility (PS) -6976 + (NN) -2234 + (LL) 220 1D Compatibility (HY) -2400 + (ID) 950 Total energy: -8539.0 ( -33.10 by residue) QMean score : 0.023

(partial model without unconserved sides chains): PDB file : Tito_4O5P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4O5P-query.scw PDB file : Tito_Scwrl_4O5P.pdb: