Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------MGKLLRKPLNERIAPGVTLVQDI-NQGNSPLSYVGF-RLI---------------ELEEDAVYQETLDGLECCIVALTGKISVSEGDHVFSEIGTRANVFEKIPTDSVFISGGR---AFQVKADAEKARVALCYSPADRNLPTTLIKASDNSIEQRGKYQ---NKRLVHNILPDVSEVASSLLVVEVYTDGGNFSSYPPHKHDHDNLPAESLLEESYYHEINPKQGFIFQRVYTDDRALDETMAVEHQNAVIVPEGYHPVGVPDGYDSYYLNVMAGPKRVWEFHNDPDHEWILERD 1X8M Chain:A ((1002-1268)) SLDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCY-EIGHR---------DALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTR---------------MEVYFYFNM-DDDACVFHMMGQPQE--TRHIVMHNEQAVISPSWSIHSGVGTK-AYTFIWGMVGENQVF---------------

General information: TITO was launched using: RESULT: Template: 1X8M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -103463 for 1786 contacts (-57.9/contact) + 2D Compatibility (PS) -24967 + (NN) -7201 + (LL) 1812 1D Compatibility (HY) -12000 + (ID) 2100 Total energy: -147919.0 ( -82.82 by residue) QMean score : 0.420

(partial model without unconserved sides chains): PDB file : Tito_1X8M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X8M-query.scw PDB file : Tito_Scwrl_1X8M.pdb: