Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKVRKSFVLLLTGLLAVLILSACGQKTQQDIVAGLDEKAKEYTSYKAKAKMTIETG--SEPQVYNVEIWHKKPSLYRVYLENPKKDQNQVILRNENGVFVLTPSLNKSFRFQSDWPNNSSQVYLFESLVKDVQNDSDAVFTAKEKKYVFETKTNYQHNKMLPTQEITFNKKDMSPSSVKVMDTDRKVMVKVEFSSFEFNKQFDKESFDEKKNMTLSQMDVATSAKPSDTFAVKTPLELPLGVKLLEEKDISTEDGKRIIMTYGGEKSFTLIQEKAQIAKASSSVTLNGEPVNLGYTIGALSDASLSWTYDGVDYLLSSKDLSKEEMVTVAKSMQGQSSK 2W7Q Chain:A ((13-201)) ----------------------GSIAIDDSAAVQRLTGLLNKAQTLTARFSQLTLDGSGTRLQETAGQLSLKRPGLFRWHTDAPN---EQLLISNGEKVWLYDPDLEQVTIQKLDQRLTQTPALLLSGDISKISESFAITYKEGGNVVDFVLKPKTKD-TLFDTLRLSFRS--GKVNDMQMIDGVGQ-RTNILFFDVKMNEALDAKQFTFDVPPGVDV--------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2W7Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 897 -57368 -63.95 -306.78 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -63.95 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.446

(partial model without unconserved sides chains): PDB file : Tito_2W7Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2W7Q-query.scw PDB file : Tito_Scwrl_2W7Q.pdb: