Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNTNYWIGVVSEQHVLKGAAGGFAQLCHGKKAPLAKMKEGDWLIYYSPRDAYPDGKLLR-SFTAIGKVKSGNIYPYQM--------APNFIPYRLDIDYYPCHKIGFYDIKSKLEFVQETKHLGFLF-RRGHFEISKKDFLTIAQAMGVNISGMAL 2HD9 Chain:A ((1-145)) --MTYWICITNRENWEVIKRHNVWGVPKKHKNTLSRVKPGDKLVIYVRQEKDKEGNLLEPKIVGIYEVTS-EPYVDFSRIFKPHRGGKETYPYRVKIKPIKIGEINFKPLINDLKFIKNKKRWSMHFFGKAMRELPEEDYKLIEKLLL--------

General information: TITO was launched using: RESULT: Template: 2HD9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 587 -85859 -146.27 -635.99 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -146.27 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.401

(partial model without unconserved sides chains): PDB file : Tito_2HD9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HD9-query.scw PDB file : Tito_Scwrl_2HD9.pdb: