Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLNIKSDRIMTSDPQKFTVDGVRFFQQYLNKIRPDAMEIDNLIINSDIIKEDLIVHVSKMIDRLALYDLHRKRSIDKHFSAAFTV---DIN----DREEFYSANIADVSIDLNESSGV 1TDP Chain:A ((1-111)) -MDIKSQTLYLNLSEAYKDPEVK----ANEFLSKLVVQCAGKLTASNS-ENSYIEVISLLSRGISSYYLSHKRIIPSSMLTIYTQIQKDIKNGNIDTEKLRKYEIAKGLMSVPYIYF-

General information: TITO was launched using: RESULT: Template: 1TDP.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 414 -33235 -80.28 -319.56 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -80.28 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.283

(partial model without unconserved sides chains): PDB file : Tito_1TDP.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1TDP-query.scw PDB file : Tito_Scwrl_1TDP.pdb: