Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METIIIALIAFIIGIIAIPIVLFAWIYIKDEKQQEHSILRNYPVIGRFRYILEKIGPELRQYLYSNDNEEQPFSRKEYEQTVISGKYKSRMMGFGSVRDFDKPGYYIRNAMFPKQREEMHVNQTPKIETQIYKMDADNLFKRKEHAEHIKADPYFLHPDDVQVIGEHTCEKPFYVKGLVGQSAMSYGSLGERAVTALSKGLHLAGGTWMNTGEGGLSEYHL------------------------KGGADIICQIGPGLFGVRKRNGEFSWEEFKRKSRIDQIKAFELKLAQGAKT-RGGHVDGAKVSEEVADIRNVEPGKSIDSPNRFYEFSNPPEMLDFIEKLRDVG-QKPVGIKLVAGHPEELHELFSHMQKSGKHPDFITIDGSEGGTGASFYELADTVGLPIMTALPIVDTLLKQYGLRSQLKIFASGKLLTPDKIAVALALGADFVNIARGMMFSVGCIRALVCHTNTCPAGVATTDPKLQKALSVEEKQHRVCNYVISLREGLFNLAAAAGINSPIHF-SKEHVVYRKEDGSIINIDNLIHQFVS 1OFD Chain:A ((865-1208)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIVKRFCTGGMSLGALSREAHETLAIAMNRL-GAKSNSGEGGEDVVRYLTLDDVDSEGNSPTLPHLHGLQNGDTANSAIKQIASGRFGVT-------PEYL------MSGKQLEIKMAQGAKPGEGGQLPGKKVSEYIAMLRRSKPGVTLISPPPHHDIYSIEDLAQLIYDLHQINPEAQVSVKLVAEI--GIGTIAAGVA--KANADIIQISGHDGGTGASPLSSIKHAGSPWELGVTEVHRVLMENQLRDRVLLRADGGLKTGWDVVMAALMGAEEYGFGSIAMIAEGCIMARVCHTNNCPVGVATQQERLRQRFK--GVPGQVVNFFYFIAEEVRSLLAHLGYRSLDDIIGRTDLLKVRSD---------------

General information: TITO was launched using: RESULT: Template: 1OFD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1932 -124171 -64.27 -391.71 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -64.27 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.489

(partial model without unconserved sides chains): PDB file : Tito_1OFD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OFD-query.scw PDB file : Tito_Scwrl_1OFD.pdb: