Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRNKEFDTALVLHRAIEVFGEYGYEGTSLQDLLSHLGIARQSLYDTYGTKRDLFLSAVKSYLEGKNAAVMERLEAPGSVKEAIRDIFQEGVNALRDPERAKACYIINSAIEQIPHDPELARYFERQSKQLEDAFYHGLLRAKDQGELNGEDTDISALARYLNQSRLSLTFIAKVTADMDRLQDHVDVSLSVLD 2I10 Chain:A ((12-193)) -------DDQVALQTAMELFWRQGYEGTSITDLTKALGINPPSLYAAFGSKRDLFEKTLDRYMCERTLQLEEAMVR-PTAHEAVLDFLTGRVEVFT------GCMTVQAGLASGEPHHEIVDLLTAAREQMRQTVLDRFEKALADGDLP-AGTDCTALARYVMAAVYGLSVEAASGAPREELTAAAILAAQ---

General information: TITO was launched using: RESULT: Template: 2I10.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 651 -75277 -115.63 -427.71 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -115.63 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.498

(partial model without unconserved sides chains): PDB file : Tito_2I10.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I10-query.scw PDB file : Tito_Scwrl_2I10.pdb: