Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------MLETVPVRCVERKITSLVVDLSGVPIVDTMVAQQLYNLSKTLFLLGVKAVFSGIRPDVAQTSIQL-GLDFSE-YETYGTLKQALENMGVRCIVEELEENK 2VY9 Chain:A ((6-119)) PILKVDDYWVVAIEETLHDQSVIQFKEELLHNITGVAGKGLVIDISALEVVDSFVTRVLIEISRLAELLGLPFVLTGIKPAVAITLT-EMGLDLRGMA-TALNLQKGLDKLKNL--------AR

General information: TITO was launched using: RESULT: Template: 2VY9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 300 -64758 -215.86 -735.89 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -215.86 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_2VY9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VY9-query.scw PDB file : Tito_Scwrl_2VY9.pdb: