Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANQHFAKEAPETYWKTSTDLPSFPALQEDTECDVTIIGGGITGITTAYELTKRGFRVVLIEANQVLNGTTAHTTAKVTAQHDMIYDEFIRHFGLNHARLYYEANQNAIDYIKGIVDEHQIDCEWIEQDAYLYTANENAVQKIHTEHEAYTKLGIERDLIKDLPI----P----LGSKLALVMKNQAQFHPLQYLKALLEQIVQKGGRIYEETVALDIK-KGERPEVVTKSRHAIKSRFIICCSHFPFYDGG--GL--YAARMYSDRSYVLAIKPKIE-YPEGMYLSIDQPSVALRYTVVNGEKLILFSGVSHKTGQ--GKAMSTHYETLRQLAESTIGIE---SIPYYWSTQDLVTIDKIPFIGPMSENEDNILVATGFKKWGMTSSAVAATLLSDLVEKKEN-PYESIFTPSRFHLNPGLQKVISYNADVAKHLIKGKLEKPDVQFEDISPGEGKAVTINGRRAGAFRDETGCLHLVDTTCTHLGCEVEWNDSEHTWDCPCHGSRFKPSGEVVEGPAIKPLKQIDLD 1Y56 Chain:B ((3-374)) -----------------------------PEKSEIVVIGGGIVGVTIAHELAKRGEEVTVIEKRFIGSGSTFRCGTGIRQQFN--------------DEANVRVMKRSVELWKKYSEEYGF--SFKQTGYLFLLYDDEEVKTFKRNIEIQNKFGVPTKLITPEEAKEIVPLLDISEVIAASWNPTDGKADPFEATTAFAVKAKEYGAKLLEYTEVKGFLIENNEIKGVKTNKGIIKTGIVVNATNAWANLINAMAGIKTKIPIEPYKHQAVITQPIKRGTINPMVISFKYGHAYLTQTF--H-GGIIGGIGYEIGPTYDLTPTYEFLREVSYYFTKIIPALKNLLILRTWAGYYAKTPDSNPAIGRIEE-LNDYYIAAGFSGHGFMMAPAVGEMVAELITKGKTKLPVEWYDPYRFERGEL------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1Y56.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2142 -206796 -96.54 -587.49 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.65 3D Compatibility (PKB) : -96.54 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.479

(partial model without unconserved sides chains): PDB file : Tito_1Y56.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y56-query.scw PDB file : Tito_Scwrl_1Y56.pdb: