Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKVRTKDVMEQFNLELISGEEGINRPITMSDLSRPGIEIAGYFTYYPRERVQLLGKTELSFFEQLPEEEKKQRMDSLCTDVTPAIILSRDMPIPQELIDASEKNGVPVLRSPLKTTRLSSRLTNFLESRLAPTTAIHGVLVDIYGVGVLITGKSGVGKSETALELVKRGHRLVADDCVEIRQEDQDTLVGNAPELIEHLLEIRGLGIINVMTLFGAGAVRSNKRITIVMNLELWEQGKQYDRLGLEEETMKIIDTEITKLTIPVRPGRNLAVIIEVAAMNFRLKRMGLNAAEQFTNKLADVIEDGEQEE 1KO7 Chain:A ((1-298)) --MLTTKSLVERFELEMIAGEAGLNKQIKNTDISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDEERKGRMRKLCRPETPAIIVTRDLEPPEELIEAAKEHETPLITSKIATTQLMSRLTTFLEHELARTTSLHGVLVDVYGVGVLITGDSGIGKSETALELIKRGHRLVADDNVEIREISKDELIGRAPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRLRLNIHLE-------------NEETLRILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFNDRLN----------

General information: TITO was launched using: RESULT: Template: 1KO7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1401 -160305 -114.42 -562.47 target 2D structure prediction score : 0.51 Monomeric hydrophicity matching model chain A : 0.89 3D Compatibility (PKB) : -114.42 2D Compatibility (Sec. Struct. Predict.) : 0.51 1D Compatibility (Hydrophobicity) : 0.89 QMean score : 0.607

(partial model without unconserved sides chains): PDB file : Tito_1KO7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KO7-query.scw PDB file : Tito_Scwrl_1KO7.pdb: