Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAVQARINQLIEAGVIEKFTAVINPAKIGIHVSVFFNVEVEPQFLEEVALKLEEEPAVTSLYHMTGPSKLHMHGIFTNDQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL 2ZNY Chain:C ((25-163)) -----------LDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFL-DLIGSIPGVEGTHTMIVLKTHK-------

General information: TITO was launched using: RESULT: Template: 2ZNY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 460 -92810 -201.76 -667.69 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain C : 0.77 3D Compatibility (PKB) : -201.76 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.648

(partial model without unconserved sides chains): PDB file : Tito_2ZNY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZNY-query.scw PDB file : Tito_Scwrl_2ZNY.pdb: