Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYK--------GQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRT--PSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG 4BVN Chain:A ((15-284)) -------SLLMALVVLLIVAGNVLV-IAAIGSTQRLQTLTNLFITSLACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASVETLCVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQALKCYQDPGCCDF--VTNRAYAIASSIISFYIPLLIMIFV---ALRVYREAKEQIR----------KRKTSRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPKWLFVAFNW-LGYANSAMNPIILCRSPDFRKAFKRLLA-----------------------------------------

General information: TITO was launched using: RESULT: Template: 4BVN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -228422 for 1868 contacts (-122.3/contact) + 2D Compatibility (PS) -26142 + (NN) -11976 + (LL) 5452 1D Compatibility (HY) -27600 + (ID) 3750 Total energy: -292438.0 ( -156.55 by residue) QMean score : 0.438

(partial model without unconserved sides chains): PDB file : Tito_4BVN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BVN-query.scw PDB file : Tito_Scwrl_4BVN.pdb: