Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKPDIINPNFSVWVNASAGTGKTKILIDRVLRLLLENKRNIFCLTFTNAAANEMESRIHNILSKWAVCSDNELIASLEQLDLSLLLLQHHYPPSHPFLSSQCLTLRSRWPQTKNSEVFNHYLIQARRLFSELENLDLTIQTVHAFCYKLISSFPAEAGIVPNCTLSECKELHSIVFDKLLHNEAVQDSIKFIAAEVDENKLRDLLYTLCIKRSVSANNLEYVKGKLSAPDEIHGLQSEATEQIERLAEILSKGSKRDRNYSKMLDLTSSSFIQVADTRIQKLDSSATRWNDISIENLVKVFLKSESCEKKSISSIITKSTLEKFPGAEQVIENIQNAVFTHVRDINSYQIFKRTSSFLDIFKVYIDLYNSEKSKNALLDYNDIIDLATNLLSNPDY--KNWVLFNLDQKIDHILVDEAQDNSISQWKIIANLCDEFFIRNDEKRTLFVVGDVKQSIYRFQGANPHLFNCMQQYFHTKSGGKDWISCQLEKSFRSTPETLTLVDRLFNNFREEIS--FVDSEIKHIPYR----ENDQGYVEIWPLLPRCKEEEQQALQIHLMHRKDYIITDRLLAQAIAHKIHNWLNEGRIL-VAKNRHIEPRDIMILVRQRNMLVDYVISELKKANIPVVGRDYFRIMDYIAVQDLIALTEFLLLPTNDLALANALKSPLFNFTEDDLFNIAYDRKEQSLWERLQN----------Y--SE-DIYSKLNDLINLSHIESPLTLFTHILR--TGKKKFAARLGL-ECFEVLDEFMNLVLQFENP---SLQAFVQWIKENNPEI-KNDMQSERNAVRIMTIHKSKGLQAPIVFLVDTNTVPKNSE---SIVLDAMGAPF---LCGK-N---NNAYCDQVKREKKLEDYNEYLRLLYVALTRAEDELYILGKEPVQ-------------------------KGSWYDIITKYGEPYEKKYMELHQIFKEK-VEVLCVNANYPY-IYKKRDYFNI--------PAVLPPP---------NLSILFQHSPSPSQ-YPLLSPQCFDTGIHSFSPLDSSVTHWDDK-----KRNTWMTDGYTRGLIIHSILQYMPKIEKDRRKNWIGKYLDNINIR---------KN-KDEIYRKILAFNEKYDYLF-DLDGKSEITLSGTI-------------NGKPVLVRLDKLCITQDKAIIIDYKSHRNVSV------SSL-NEIKKQMLIYKTLVQEICPNKQVECMVIWVEDLTIQSDF 3U4Q Chain:A ((345-1230)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVQLVISYGKRFEAAKQEKSIIDFSDLEHYCLAILTAENDREPSEAARFYQEQFHEVLVDEYQDTNLVQESILQLVTSGPE----ETGNLFMVGDVKQSIYRFRLAEPLLFLSKYKRFTESG-EGTGRKIDLNKNFRSRADILDSTNFLFKQLMGGKIGEVDYDEQAELKLGAAYPDNDETETE------------LLLID---------LETVQFEAKAIAKEIRKLISSPFKVYKKTHRNIQYRDIVILLRSMPWA-PQIMEELRAQGIPVYANLTSGYFEAVEVAVALSVLKVIDNPYQDIPLASVLRSPIVGADENELSLIRLENKKAPYYEAMKDYLAAGDRSDELYQKLNTFYGHLQKWRAFSKNHSVSELIWEVYRDTKYMDYVGGMPGGKQRQANLRVLYDRARQYESTAFRGLFRFLRFIERMQERGD------QEDVVRLMTIHSSKGLEFPVVFVAGLGRNFNMMDLNKSYLLDKELGFGTKYIHPQLRISYPTLPLIAMKKKMRRELLSEELRVLYVALTRAKEKLFLIGSCKDHQKQLAKWQASASQTDWLLPEFDRYQARTYLDFIGPALARHR----------HADISGHPARFAVQMIHSYD------SERLEAIRRGEPV---FAFDEKAREQLSWTY-PHQEVTQIRTKQSVS-----------DEYSGR-----YRRPAFMMKKGLTAAEKGTAMHTVMQHIPLSHVPS-IEEAEQTVHRLYEKELLTEEQKDAIDIEEI-VQFFH-TEIGGQLIGAKWKDREIPFSLALPAKEIYPDAHEADEPLLVQGIIDCLYETEDGLYLLAYKSDRIEG-GFEGAAPILKKRYETQIQLYTKAVEQIAKTKVKGCALYFFDGGHILTL-

General information: TITO was launched using: RESULT: Template: 3U4Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -259885 for 4747 contacts (-54.7/contact) + 2D Compatibility (PS) -72635 + (NN) -22712 + (LL) 31024 1D Compatibility (HY) -29200 + (ID) 7850 Total energy: -361258.0 ( -76.10 by residue) QMean score : 0.409

(partial model without unconserved sides chains): PDB file : Tito_3U4Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3U4Q-query.scw PDB file : Tito_Scwrl_3U4Q.pdb: