Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKSFCVKAPAKINLFLHVVEKKETGYHLIEGLFVFANLSNFLEIKVGEKDFRYDNPIVEFVNSELKISNKYNTVMRAVNLLLRHAPVRTKVTVKVVKNIPTSAGLGSGSSDAGAVIRTLGKLWKIDRPI----LNEIALSVGADVPASIDSKPVLVRGIGEELCYINKFSLPTNIVLAKPKKKFLSTPEVFSKYG-GNFSKPIEWRDDTEKDLLKLLKETENDLQEIAISLVPEIRDVILALESQEGSILSRMSGSGVTCFGIFDSEENAKTAAVNIREKQPEWWVCDAQLIV 2V8P Chain:A ((7-271)) -----VLSPAKINLGLWVLGRLPSGYHEI--LTLYQEIPFYDEIYIREGVLR--------VETNIGIPQEENLVYKGLREFERITGIEINYSIFIQKNIPPGAGLGGGSSNLAVVLKKVNEL--LGSPLSEEELRELVGSISADAPFFLLGKSAIGRGKGEVLEPVET-EISGKITLVIPQVSS-STGRVYSSLREEHFVTPEYAEEKIQRIISGEVEEIENVLGDIARELYPEINEVYRFVEYL--GFKPFVSGSGSTVYFFGGASEELKKAA-----KMRGWKVVELEL--

General information: TITO was launched using: RESULT: Template: 2V8P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -132040 for 2216 contacts (-59.6/contact) + 2D Compatibility (PS) -27928 + (NN) -3955 + (LL) 2168 1D Compatibility (HY) -16400 + (ID) 4150 Total energy: -182305.0 ( -82.27 by residue) QMean score : 0.440

(partial model without unconserved sides chains): PDB file : Tito_2V8P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2V8P-query.scw PDB file : Tito_Scwrl_2V8P.pdb: