Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPISLPKVRGIYRYSVLMSKITWLNVGGQADILFKPRDIEDLIYLIK---NTKLPISVIGATSNMIVRDSGIRGITVKLGKEFAYIKYKSNNSIIAGGAALLSNLAYFAGEQQVSGLEFLVGIPGTIGGGIEMNAGAYGSDVASVVQSIKAVNLSDGNLYEFSSKEMGYVYRGHSL-KGQWIFIEAEFKGVSSGHEVILHRLKEIINKKNKSQPVRGKTAGCIFKNPRAYQAWKLIDGSGCRGLNNGGAKISKKHCNFLLNYNNATASDLENLGNKVRNTVKDKFNIELEWEIRVLGSH 1HSK Chain:A ((37-315)) -----------------LKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISL-LSLDHIEV-SDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVN-EQGSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEH

General information: TITO was launched using: RESULT: Template: 1HSK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -182801 for 2325 contacts (-78.6/contact) + 2D Compatibility (PS) -29374 + (NN) -9695 + (LL) 1360 1D Compatibility (HY) -22400 + (ID) 4900 Total energy: -247810.0 ( -106.58 by residue) QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_1HSK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1HSK-query.scw PDB file : Tito_Scwrl_1HSK.pdb: