Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MISTSEHSIFKNPAKNDGLRVRTIEVSEKFTSSAQNSDTIKKVVSQNNGHVLPIIAQFLLDNTNDVTSLFQKEDSVFYQLLSTESSNTGIRMIKHYATLTTTAHILNQSLDLQLNVSSIKNYLLSYHNETVSERSLADKAMDTIVQFIAENLGKFSQQTR------LANMIQNFGILSLKDDYIEVKIIRNVFDKMLTDSQFEDTKNVIDALDNAGKL--VSDRDRKTTKRNAKDDTGKSTSLVFYQIKIDLDYADVLGLQSQGRDNVIQKHSNPSQFKNTNLEEFMKSENTTLIVF 1D8V Chain:A ((76-236)) --------------------------------------------------------------TRDVSYFFKESPPEAYNILFKGTRKITLPYTGNYENLQTAAHKIRENIDLGLPALSSAITTLFYYNA-----QSAPSALLVLIQTTAEA-ARFKYIERHVAKYVATNFKPNLAIISLENQWSALS--KQIF---LAQNQGGKFRNPVDLIKPTGERFQVTNVDSDVVKGNIK---------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1D8V.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 21439 for 1044 contacts (20.5/contact) + 2D Compatibility (PS) -15460 + (NN) 2676 + (LL) 8716 1D Compatibility (HY) -6400 + (ID) 2050 Total energy: 8921.0 ( 8.55 by residue) QMean score : 0.136

(partial model without unconserved sides chains): PDB file : Tito_1D8V.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1D8V-query.scw PDB file : Tito_Scwrl_1D8V.pdb: