Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNRIGFIGAGNMGTAMIRGLAQANLVKREEIIVGGRNLEKLKPLEAEFTGLQITTDTEKLVEQADIIILAVKPYTIPEILTSVKEKLTPDKIIISVAAGVTIQDLEELTSA---KTKIVRVMPNTPALVGEAMSSVSPNTNVTSEELKEVTAIFTSFGEAEVVSENLMDAVIGVSGSSPAYVYMFIEALADGAVLSGMPRDKAYKFAAQAVLGAAKTVLETGEHPGKLKDMVTSPGGTTIEAVKSLENDGFRSAVINAVQAAAKKNSSM 2IZZ Chain:D ((25-290)) ---VGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTREL

General information: TITO was launched using: RESULT: Template: 2IZZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -134333 for 2032 contacts (-66.1/contact) + 2D Compatibility (PS) -28568 + (NN) -8443 + (LL) 228 1D Compatibility (HY) -20400 + (ID) 5100 Total energy: -196616.0 ( -96.76 by residue) QMean score : 0.487

(partial model without unconserved sides chains): PDB file : Tito_2IZZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IZZ-query.scw PDB file : Tito_Scwrl_2IZZ.pdb: