Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEHLPEQYRQLFPTLQTHTMLASCSQSALAEPVSRAIQDYYDSLLYKGT-NWK---EAIEKTEFARNEFAKLIGAEPDEVAIVPSVSDALVSVASSLTAFGKKHVVYTDMDFPAVPHVWQAHS---DYTVSVIPS-ID-GVLPLE-QYETHISDETVLTCVPHVHYRDGYVQDIKAIAEISQRK----GSLLFVDAYQSAGHIPIDVKEWGVDMLAAGTRKYLLGIPGVAFLYVRKELADALKPKASAWFGRESGF---DGAYAKVARRFQTGTPAFISVYAAAAALSLLNHIGV-SHIRDHVKTICADAVQYAAEK-GLQLAAAQGGIQPGMVAIRDER---ASETAGLLKKKKVICAPR--ENVIRLAPHFYNTKEEMRHAIDEIAAKTIHK 1ELU Chain:A ((10-388)) ----------QFPGLANKTYFNFGGQGILPTVALEAITAMYGYLQENGPFSIAANQHIQQLIAQLRQALAETFNVDPNTITITDNVTTGCDIVLWGLDWHQGDEILLTDCEHPGIIAIVQAIAARFGITYRFFPVAATLNQGDAAAVLANHLGPKTRLVILSHLLWNTGQVLPLAEIMAVCRRHQGNYPVRVLVDGAQSAGSLPLDFSRLEVDYYAFTGHKWFAGPAGVGGLYIHGDCLGEINPTYVGWRSITYGAKGEPTGWAEGGKRFEVATSAYPQYAGLLAALQLHQRQGTAEERYQAICQRSEFLWRGLNQLPHVHCLATS-APQAGLVSFTVDSPLGHRAIVQKLEEQRIYLRTIADPDCIRACCHYITDEEEINHLLARLADF----

General information: TITO was launched using: RESULT: Template: 1ELU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2007 -287389 -143.19 -809.55 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -143.19 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.468

(partial model without unconserved sides chains): PDB file : Tito_1ELU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1ELU-query.scw PDB file : Tito_Scwrl_1ELU.pdb: