Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLSLFIIAVLMPVILLSACSDHAEEHASINTKKTVENITDVRKTAKTSIDWTKPSGGEYPDIKQKHVWIDVNVKEQKAYIKEGSNTIYTMMISSGLDQTKDDATPKGTFYVEPERGEWFFSE-G----------YQEGAEYWVSWKNHGEFLFHSVPMTKDQKVIKTEAEKLG-TKASHGCIRLTIPDAKWVYENIPEHTKVVIS 4JMN Chain:A ((123-250)) -----------------------------------------------------------------DALIGVASISAHTFTVSRNGEVLRTMPASLGKPS---RPTPIGSFHAMSKERTVVMDSRTIGIPLNSSDGYLLTAHYAVRVTWSG-VYVHSAPWSV---------NSQGYANVSHGCINLSPDNAAWYFDAVTVGDPIEVV

General information: TITO was launched using: RESULT: Template: 4JMN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 620 -72867 -117.53 -628.16 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -117.53 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.376

(partial model without unconserved sides chains): PDB file : Tito_4JMN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4JMN-query.scw PDB file : Tito_Scwrl_4JMN.pdb: